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The choice of an interval of 45 minutes between baseline and second examination in group 1 and 3 was based on a general estimate of the time necessary to reach the peak plasmatic concentration of caffeine after oral assumption, but a considerable inter-individual variability in caffeine kinetics exists [34]

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Nearly 55% of youth (ages 13-25 years old) who vape, also use cigarettes or another type of tobacco product (dual use)